{"id":6909,"date":"2026-01-13T10:56:03","date_gmt":"2026-01-13T09:56:03","guid":{"rendered":"https:\/\/mediconomics.com\/?post_type=glossary&#038;p=6909"},"modified":"2026-07-13T19:08:59","modified_gmt":"2026-07-13T17:08:59","slug":"hazard-ratio","status":"publish","type":"glossary","link":"https:\/\/mediconomics.com\/en\/glossar\/hazard-ratio\/","title":{"rendered":"Hazard Ratio"},"content":{"rendered":"<p class=\"wp-block-paragraph\">The Hazard Ratio is a statistical measure from survival analysis that expresses the relative risk of an event (e.g. death or recurrence) in one group compared with a control group over a period of time. An HR of 0.7, for example, means a 30% reduction in risk through the therapy under investigation.<br \/>Unlike the pure survival rate, the HR takes into account the entire time course of the events. It is the standard endpoint in oncology and cardiology for demonstrating the superiority of a new treatment. Biostatisticians usually calculate the HR using Cox regression models, taking confounding factors into account.<br \/>For CROs, the precise interpretation of the HR and its associated confidence interval is crucial for the Clinical Study Report (CSR). A statistically significant HR is often a prerequisite for authorisation. Graphical presentation is usually done via Kaplan-Meier curves, which make the treatment effect visually comprehensible.<\/p>\n<p><a href=\"https:\/\/mediconomics.com\/en\/glossary\/\">Back to overview<\/a><\/p>\n","protected":false},"excerpt":{"rendered":"<p>The Hazard Ratio is a statistical measure from survival analysis that expresses the relative risk of an event (e.g. death or recurrence) in one group compared with a control group over a period of time. An HR of 0.7, for example, means a 30% reduction in risk through the therapy under investigation.Unlike the pure survival [&hellip;]<\/p>\n","protected":false},"author":10,"featured_media":0,"parent":0,"template":"","meta":{"_acf_changed":false,"site-sidebar-layout":"default","site-content-layout":"","ast-site-content-layout":"default","site-content-style":"default","site-sidebar-style":"default","ast-global-header-display":"","ast-banner-title-visibility":"","ast-main-header-display":"","ast-hfb-above-header-display":"","ast-hfb-below-header-display":"","ast-hfb-mobile-header-display":"","site-post-title":"","ast-breadcrumbs-content":"","ast-featured-img":"","footer-sml-layout":"","ast-disable-related-posts":"","theme-transparent-header-meta":"","adv-header-id-meta":"","stick-header-meta":"","header-above-stick-meta":"","header-main-stick-meta":"","header-below-stick-meta":"","astra-migrate-meta-layouts":"set","ast-page-background-enabled":"default","ast-page-background-meta":{"desktop":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"ast-content-background-meta":{"desktop":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"tablet":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""},"mobile":{"background-color":"var(--ast-global-color-5)","background-image":"","background-repeat":"repeat","background-position":"center center","background-size":"auto","background-attachment":"scroll","background-type":"","background-media":"","overlay-type":"","overlay-color":"","overlay-opacity":"","overlay-gradient":""}},"footnotes":""},"glossary-cat":[],"class_list":["post-6909","glossary","type-glossary","status-publish","hentry"],"acf":[],"related_terms":"","external_url":"","internal_reference_id":"","_links":{"self":[{"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/glossary\/6909","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/glossary"}],"about":[{"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/types\/glossary"}],"author":[{"embeddable":true,"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/users\/10"}],"version-history":[{"count":1,"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/glossary\/6909\/revisions"}],"predecessor-version":[{"id":6910,"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/glossary\/6909\/revisions\/6910"}],"wp:attachment":[{"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/media?parent=6909"}],"wp:term":[{"taxonomy":"glossary-cat","embeddable":true,"href":"https:\/\/mediconomics.com\/en\/wp-json\/wp\/v2\/glossary-cat?post=6909"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}